Evaluation of liver and kidney function in favism patients

نویسندگان

  • Akbar Dorgalaleh
  • Muhammad Shahid Shahzad
  • Mohammad Reza Younesi
  • Esmaeil Sanei Moghaddam
  • Mohammad Mahmoodi
  • Bijan Varmaghani
  • Zahra Kashani Khatib
  • Shaban Alizadeh
چکیده

BACKGROUND G6PD deficiency is the most common enzymopathy of red blood cells. The clinical symptoms of favism are jaundice, hematuria and haemolytic anaemia that seem to affect liver and kidney in long term. Thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a high rate of fava beans cultivation. METHODS This study was performed on favism patients and healthy controls referring to Iranshahr central hospital. Liver and kidney function tests were performed. RESULTS The results showed a statistically significant difference between these two groups (p <0.05) for liver function tests, (AST, ALT and ALP), but not for renal tests (BUN and creatinine) (p >0.05). CONCLUSION Due to abnormalities were seen in the liver function tests of these patients, we suggest that these tests be regularly performed for favism patients who are constantly exposed to oxidant agents.

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Evaluation of liver and kidney function in favism patients

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عنوان ژورنال:

دوره 27  شماره 

صفحات  -

تاریخ انتشار 2013